Finasteride 0.1% 60ml topical

Dutasteride 0.25%

From £64.99

Dutasteride  is used for hair loss, in the treatment of male pattern baldness. It helps by blocking androgens (DHT) that cause hair to thin and shorten.

Active Ingredient: Dutasteride

Dosage: 1ml per day

Products will last: 2 months

Dutasteride works for hair loss in a very similar way to finasteride, but it is stronger and more comprehensive at blocking the hormone responsible for male-pattern baldness.

What Causes Hair Loss

Most male-pattern hair loss (androgenetic alopecia) is caused by dihydrotestosterone (DHT).

  • Testosterone is converted into DHT by an enzyme called 5-alpha reductase
  • DHT binds to genetically sensitive hair follicles
  • Follicles shrink (miniaturise) → hair becomes thinner → growth eventually stops

How Dutasteride Works

Dutasteride is a 5-alpha reductase inhibitor, but unlike finasteride, it blocks both forms of the enzyme alpha Reductase

Key Difference between Dutasteride and Finasteride

  • Finasteride: blocks Type II only
  • Dutasteride: blocks Type I and Type II

Result:

  • ~90–95% reduction in DHT
  • More complete suppression of DHT in the scalp

This stronger DHT reduction makes dutasteride more effective at stopping hair loss in many men.

Effects on Hair

  • Slows or halts further hair loss
  • Can thicken miniaturised hairs
  • Particularly effective for crown and mid-scalp
  • Often used when finasteride is insufficient

It does not revive follicles that are completely dead.

When Results Appear

  • 3–4 months: reduced shedding
  • 6–9 months: visible thickening
  • 12 months: peak results

Consistency is critical.

How It’s Taken

  • Typical dose for hair loss (off-label): 0.5 mg once daily
  • Available orally and topically
  • Dutasteride is officially approved for benign prostatic hyperplasia, not hair loss (hair use is off-label but common)

Side Effects & Safety

Side effects are similar to finasteride but may occur slightly more often due to stronger DHT suppression:

  • Reduced libido
  • Erectile dysfunction
  • Ejaculation changes
  • Mood changes (rare)

Important difference:

  • Dutasteride has a very long half-life (~5 weeks)
  • Side effects may take longer to resolve after stopping

Reported side-effect rates remain low (≈2–5%) in studies.

Who Should Consider Dutasteride

✅ Men with aggressive or progressing hair loss

✅ Those who didn’t respond well to finasteride

❌ Those concerned about stronger hormonal suppression

❌ Women (especially pregnancy risk)

Best Results When Combined With

  • Minoxidil (topical or oral)
  • Microneedling
  • Ketoconazole shampoo
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